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UNAIDS is greatly encouraged by news of a possible cure of an HIV-positive man

March 5, 2019

SEATTLE/GENEVA, 5 March 2019—UNAIDS is greatly encouraged by the news that an HIV-positive man has been functionally cured of HIV. The man was treated by specialists at University College London and Imperial College London for advanced Hodgkin’s lymphoma in 2016 using stem cell transplants from a donor who carried a rare genetic mutation. Researchers report that HIV has been undetectable in the man since he stopped taking antiretroviral medicine 18 months ago.

“To find a cure for HIV is the ultimate dream,” said Michel Sidibé, Executive Director of UNAIDS. “Although this breakthrough is complicated and much more work is needed, it gives us great hope for the future that we could potentially end AIDS with science, through a vaccine or a cure. However, it also shows how far away we are from that point and of the absolute importance of continuing to focus HIV prevention and treatment efforts.”

Stem cell transplants are highly complex, intensive and costly procedures with substantial side-effects and are not a viable way of treating large numbers of people living with HIV. However, the results do offer a greater insight for researchers working on HIV cure strategies and highlight the continuing importance of investing in scientific research and innovation.

The result, reported at the Conference on Retroviruses and Opportunistic Infections in Seattle, United States of America, is one of only two cases of reported functional cures for HIV. The first was the case of the Berlin patient, Timothy Ray Brown, who received similar treatment for cancer in 2007.

There is currently no cure for HIV. UNAIDS is working to ensure that all people living with and affected by HIV have access to life-saving HIV prevention, treatment, care and support services. In 2017, there were 36.9 million people living with HIV and 1.8 million people became newly infected with the virus. In the same year, almost 1 million people died of AIDS-related illnesses and 21.7 million people had access to treatment.

UNAIDS

The Joint United Nations Programme on HIV/AIDS (UNAIDS) leads and inspires the world to achieve its shared vision of zero new HIV infections, zero discrimination and zero AIDS-related deaths. UNAIDS unites the efforts of 11 UN organizations—UNHCR, UNICEF, WFP, UNDP, UNFPA, UNODC, UN Women, ILO, UNESCO, WHO and the World Bank—and works closely with global and national partners towards ending the AIDS epidemic by 2030 as part of the Sustainable Development Goals. Learn more at unaids.org and connect with us on Facebook, Twitter, Instagram and YouTube.

Source: UNAIDS

WHAT IS PANCAP?

PANCAP is a Caribbean regional partnership of governments, regional civil society organisations, regional institutions and organisations, bilateral and multilateral agencies and contributing donor partners established on 14 February 2001.  PANCAP provides a structured and unified approach to the Caribbean’s response to the HIV epidemic, and coordinates the response through the Caribbean Regional Strategic Framework on HIV and AIDS to maximise efficient use of resources and increase impact, mobilise resources and build the capacity of partners.

What are the Global AIDS Strategy 2021–2026 targets and commitments?

If targets and commitments in the strategy are achieved:

  • The number of people who newly acquire HIV will decrease from 1.7 million in 2019 to less than 370 000 by 2025
  • The number of people dying from AIDS-related illnesses will decrease from 690 000 in 2019 to less than 250 000 in 2025.
  • The goal of eliminating new HIV infections among children will see the number of new HIV infections drop from 150,000 in 2019 to less than 22,000 in 2025.

What are the 95-95-95 Targets for ending AIDS?

  • 95% of People Living with HIV know their HIV status;
  • 95% of people who know their status on treatment; and
  • 95% of people on treatment with suppressed viral loads.

HELPFUL LINKS:

Global AIDS Strategy 2021–2026, End Inequalities, End AIDS
https://pancap.org/pancap-documents/global-aids-strategy-2021-2026-end-inequalities-end-aids/

Caribbean Regional Strategic Framework on HIV and AIDS (CRSF) 2019-2025
https://pancap.org/pancap-documents/caribbean-regional-strategic-framework-2019-2025/